The Retina Reference

Choroidal Melanoma - Partial Regression After Transpupillary Thermotherapy

You should look at the Normal Retina photo first for comparison. This photo shows the appearance of a choroidal melanoma after one treatment using Transpupillary Thermotherapy (TTT), a form of laser treatment in which the tumor is heated approximately 10 degrees centigrade leading to induction of heat shock proteins and tumor cell death. The appearance of the tumor shown here before the TTT can be seen by looking at the Choroidal Melanoma photo. The shrinkage is apparent. This tumor was treated both with TTT and Iodine 125 plaque therapy, a form of combined treatment called sandwich therapy, since the plaque treatment works from the outside in and the TTT from the inside out. More information can be found under Choroidal Melanoma in the Information section of the website.