The Retina Reference

Behcet's Disease with Retinitis Responsive to Prednisone and Adalimumab

This 20 year old woman had Behcet's disease with retinitis that responded rapidly to oral prednisone and subcutaneous injection of adalimumab. A - Initial fundus appearance of retinitis. The yellow arrow indicates white paravascular retinitis. Subretinal fluid is present but is difficult to appreciate in this photograph (see OCT, panel C). B - One month after beginning oral prednisone 40 mg/day and after one injection of subcutaneous adalimumab, the retinitis has regressed, as has the subretinal fluid. The blue arrow indicates residual retinal pigment epithelial metaplastic changes. C - An optical coherence tomograph line scan showing the retinal edema and subretinal fluid (orange arrow) at the initial presentation. D - One month after treatment, the edema and subretinal fluid have resolved. The retinal pigment epithelial metaplasia is indicated by the red arrow.