The Retina Reference

Comparison of Hydroxychloroquine Keratopathy and Amiodarone Keratopathy

Hydroxychloroquine keratopathy is rarely seen. Amiodarone keratopathy is commonly seen by ophthalmologists and optometrists. The two conditions do not look alike, and therefore a side-by-side comparison may be educational. Hydroxychloroquine keratopathy is shown in panel A and amiodarone keratopathy in panel B. The corneal deposits in hydroxychloroquine keratopathy are more diffusely distributed (white arrows), whereas in amiodarone keratopathy they take the appearance of a whisk broom, a vortex, or a horse's tail (yellow arrow).