Polypoidal Choroidal Vasculopathy - Over a course of 7 years

This 69-year-old African American female has been followed for 7 years for polypoidal choroidal vasculopathy (PCV), a disease that causes choroidal neovascularization. In 2010, she presented with intermittent decreased vision in the right eye that had been worsening over a period of one year. Her vision was 20/400 in the right eye and 20/20 in the left. Fundus examination revealed active polypoidal lesions in both eyes (green arrows). Optical coherence tomography showed a disciform scar in her right macula (red arrow) and a large pigment epithelial detachment in her left eye (blue arrow). Yellow arrows point to subretinal fluid caused by leaking choroidal vessels and a white arrow shows an intraretinal cyst. She underwent a series of intravitreal avastin injections to both eyes and subsequent photodynamic therapy laser in the left to prevent further vision loss. In early 2017, the polypoidal lesions were inactive bilaterally with no accumulation of subretinal fluid as shown in the OCTs. In 2017, her visual acuity was hand motions in the right eye and 20/70 in the left.