Stargardt Disease - No Flecks

You should look at the Normal Retina photo first for comparison. Also look at the other photo of Stargardt Disease. That one shows a macula that has tan colored pigment flecks in addition to the retinal pigment epithelial atrophy. The photo shown here is of a case without the flecks. The macular retinal pigment epithelial atrophy in this case has a beaten bronze appearance that is characteristic of Stargardt Disease in some cases. Both types of fundus appearances can be seen in this disease. It is unknown why certain cases look one way and others the other way, but presumably there are some genetic differences in the particular mutations responsible or in the interplay with other genes or the environment.