Comparison of Hydroxychloroquine Keratopathy and Amiodarone Keratopathy

Hydroxychloroquine keratopathy is rarely seen. Amiodarone keratopathy is commonly seen by ophthalmologists and optometrists. The two conditions do not look alike, and therefore a side-by-side comparison may be educational. Hydroxychloroquine keratopathy is shown in panel A and amiodarone keratopathy in panel B. The corneal deposits in hydroxychloroquine keratopathy are more diffusely distributed (white arrows), whereas in amiodarone keratopathy they take the appearance of a whisk broom, a vortex, or a horse's tail (yellow arrow).