The Retina Reference

Hydroxychloroquine Macular Toxicity

Hydroxychloroquine is an immunomodulating drug that is commonly used in treating collagen vascular diseases such as rheumatoid arthritis and systemic lupus erythematosus. It has the serious side effect that it can cause irreversible macular damage when used in toxic doses over enough time. For this reason, patients are examined at regular intervals by ophthalmologists to detect toxic dosing and early evidence of toxicity. Tests used are automated visual fields (10-2 program), multifocal electroretinography, spectral domain optical coherence tomography, and fundus autofluorescence photography.

PDF Documents: